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Modulation of Voltage- and Ca(2+)-dependent Gating of Ca(V)1.3 L-type Calcium Channels by Alternative Splicing of a C-terminal Regulatory Domain

Low voltage activation of Ca(V)1.3 L-type Ca(2+) channels controls excitability in sensory cells and central neurons as well as sinoatrial node pacemaking. Ca(V)1.3-mediated pacemaking determines neuronal vulnerability of dopaminergic striatal neurons affected in Parkinson disease. We have previousl...

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Detalles Bibliográficos
Autores principales:	Singh, Anamika, Gebhart, Mathias, Fritsch, Reinhard, Sinnegger-Brauns, Martina J., Poggiani, Chiara, Hoda, Jean-Charles, Engel, Jutta, Romanin, Christoph, Striessnig, Jörg, Koschak, Alexandra
Formato:	Texto
Lenguaje:	English
Publicado:	American Society for Biochemistry and Molecular Biology 2008
Materias:	Mechanisms of Signal Transduction
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2475692/ https://www.ncbi.nlm.nih.gov/pubmed/18482979 http://dx.doi.org/10.1074/jbc.M802254200

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