Lack of Expression of Gp-130 Makes Pancreatic Beta Cell Lines Unresponsive to the IL-6 Family of Cytokines

Cytokine receptors from the IL-6 receptor family are comprised of ligand specific α chains and a common signalling chain, gp-130, which is also required for high affinity binding. A cDNA library generated from the β-TC3 SV40 T-antigen transformed insulinoma cell line was screened for members of this...

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Detalles Bibliográficos
Autores principales: Naselli, Gaetano, Deaizpurua, Henry J., Thomas, Helen E., Johnston, Anne M., Kay, Thomas W. H.
Formato: Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2000
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2477742/
https://www.ncbi.nlm.nih.gov/pubmed/11467415
http://dx.doi.org/10.1155/EDR.2000.239

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2477742/
https://www.ncbi.nlm.nih.gov/pubmed/11467415
http://dx.doi.org/10.1155/EDR.2000.239

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