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Prevention of Diabetes in the NOD Mouse by Intra-muscular Injection of Recombinant Adeno-associated Virus Containing the Preproinsulin II Gene

Using the Adeno-associated virus (AAV) as a gene delivery vehicle, we have constructed a recombinant vector containing the full length rat preproinsulin gene (vLP-1). Utilizing the well described non-obese diabetic (NOD) mouse model, an experimental group (n=10) of animals were intramuscularly (IM)...

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Detalles Bibliográficos
Autores principales:	Jindal, Rahul M., Karanam, M., Shah, Rita
Formato:	Texto
Lenguaje:	English
Publicado:	Hindawi Publishing Corporation 2001
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2478535/ https://www.ncbi.nlm.nih.gov/pubmed/12369716 http://dx.doi.org/10.1155/EDR.2001.129

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