Substrate-induced Nuclear Export and Peripheral Compartmentalization of Hepatic Glucokinase Correlates with Glycogen Deposition

Hepatic glucokinase (GK) is acutely regulated by binding to its nuclear-anchored regulatory protein (GKRP). Although GK release by GKRP is tightly coupled to the rate of glycogen synthesis, the nature of this association is obscure. To gain insight into this coupling mechanism under physiological st...

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Detalles Bibliográficos
Autores principales: Jetton, Thomas L., Shiota, Masa, Knobel, Susan M., Piston, David W., Cherrington, Alan D., Magnuson, Mark A.
Formato: Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2001
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2478546/
https://www.ncbi.nlm.nih.gov/pubmed/12369705
http://dx.doi.org/10.1155/EDR.2001.173

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