Potentiation of Mitogenic Activity of Platelet-Derived Growth Factor by Physiological Concentrations of Insulin via the MAP Kinase Cascade in Rat A10 Vascular Smooth Muscle Cells

Hyperinsulinemia has been shown to be associated with diabetic angiopathy. Migration and proliferation of vascular smooth muscle cells (VSMC) are the processes required for the development of atherosclerosis. In this study, we attempted to determine whether insulin affects mitogenic signaling induce...

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Detalles Bibliográficos
Autores principales: Yamada, Hitomi, Tsushima, Toshio, Murakami, Hitomi, Uchigata, Yasuko, Iwamoto, Yasuhiko
Formato: Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2002
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2478577/
https://www.ncbi.nlm.nih.gov/pubmed/11991199
http://dx.doi.org/10.1080/15604280214489

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