Valine Pyrrolidide Preserves Intact Glucose-Dependent Insulinotropic Peptide and Improves Abnormal Glucose Tolerance in Minipigs With Reduced β-Cell Mass

The incretin hormones glucagon-like peptide-1 (GLP-1) and glucose-dependent insulinotropic polypeptide (GIP) are important in blood glucose regulation.However, both incretin hormones are rapidly degraded by the enzyme dipeptidyl peptidase IV (DPPIV). The concept of DPPIV inhibition as a treatment fo...

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Detalles Bibliográficos
Autores principales: Larsen, Marianne Olholm, Rolin, Bidda, Ribel, Ulla, Wilken, Michael, Deacon, Carolyn F., Svendsen, Ove, Gotfredsen, Carsten F., Carr, Richard David
Formato: Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2003
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2478600/
https://www.ncbi.nlm.nih.gov/pubmed/14630571
http://dx.doi.org/10.1155/EDR.2003.93

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