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Anti-Insulin Receptor Autoantibodies Are Not Required for Type 2 Diabetes Pathogenesis in NZL/Lt Mice, a New Zealand Obese (NZO)-Derived Mouse Strain

The New Zealand obese (NZO) mouse strain shares with the related New Zealand black (NZB) strain a number of immunophenotypic traits. Among these is a high proportion of B-1 B lymphocytes, a subset associated with autoantibody production. Approximately 50% of NZO/HlLt males develop a chronic insulin-...

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Detalles Bibliográficos
Autores principales:	McInerney, Marcia F., Najjar, Sonia M., Brickley, Deanna, Lutzke, Mary, Abou-Rjaily, George A., Reifsnyder, Peter, Haskell, Bradford D., Flurkey, Kevin, Zhang, Ying-Jian, Pietropaolo, Susan L., Pietropaolo, Massimo, Byers, James P., Leiter, Edward H.
Formato:	Texto
Lenguaje:	English
Publicado:	Hindawi Publishing Corporation 2004
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2478629/ https://www.ncbi.nlm.nih.gov/pubmed/15512785 http://dx.doi.org/10.1080/15438600490478029

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