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Nicotinic acetylcholine receptor subunit variants are associated with blood pressure; findings in the Old Order Amish and replication in the Framingham Heart Study

BACKGROUND: Systemic blood pressure, influenced by both genetic and environmental factors, is regulated via sympathetic nerve activity. We assessed the role of genetic variation in three subunits of the neuromuscular nicotinic acetylcholine receptor positioned on chromosome 2q, a region showing repl...

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Detalles Bibliográficos
Autores principales: McArdle, Patrick F, Rutherford, Sue, Mitchell, Braxton D, Damcott, Coleen M, Wang, Ying, Ramachandran, Vasan, Ott, Sandy, Chang, Yen-Pei C, Levy, Daniel, Steinle, Nanette
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2478679/
https://www.ncbi.nlm.nih.gov/pubmed/18625075
http://dx.doi.org/10.1186/1471-2350-9-67