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No Major Change in vCJD Agent Strain after Secondary Transmission via Blood Transfusion

BACKGROUND: The identification of transmission of variant Creutzfeldt-Jakob disease (vCJD) by blood transfusion has prompted investigation to establish whether there has been any alteration in the vCJD agent following this route of secondary transmission. Any increase in virulence or host adaptation...

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Detalles Bibliográficos
Autores principales: Bishop, Matthew T., Ritchie, Diane L., Will, Robert G., Ironside, James W., Head, Mark W., Thomson, Val, Bruce, Moira, Manson, Jean C.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2478718/
https://www.ncbi.nlm.nih.gov/pubmed/18682737
http://dx.doi.org/10.1371/journal.pone.0002878