Mutations in the LKB1 tumour suppressor are frequently detected in tumours from Caucasian but not Asian lung cancer patients

Somatic mutations of LKB1 tumour suppressor gene have been detected in human cancers including non-small cell lung cancer (NSCLC). The relationship between LKB1 mutations and clinicopathological characteristics and other common oncogene mutations in NSCLC is inadequately described. In this study we...

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Detalles Bibliográficos
Autores principales: Koivunen, J P, Kim, J, Lee, J, Rogers, A M, Park, J O, Zhao, X, Naoki, K, Okamoto, I, Nakagawa, K, Yeap, B Y, Meyerson, M, Wong, K-K, Richards, W G, Sugarbaker, D J, Johnson, B E, Jänne, P A
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 2008
Materias:
Clinical Study
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2480968/
https://www.ncbi.nlm.nih.gov/pubmed/18594528
http://dx.doi.org/10.1038/sj.bjc.6604469

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