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DLEC1 and MLH1 promoter methylation are associated with poor prognosis in non-small cell lung carcinoma

The significance of chromosome 3p gene alterations in lung cancer is poorly understood. This study set out to investigate promoter methylation in the deleted in lung and oesophageal cancer 1 (DLEC1), MLH1 and other 3p genes in 239 non-small cell lung carcinomas (NSCLC). DLEC1 was methylated in 38.7%...

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Detalles Bibliográficos
Autores principales:	Seng, T J, Currey, N, Cooper, W A, Lee, C-S, Chan, C, Horvath, L, Sutherland, R L, Kennedy, C, McCaughan, B, Kohonen-Corish, M R J
Formato:	Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2008
Materias:	Genetics and Genomics
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2480971/ https://www.ncbi.nlm.nih.gov/pubmed/18594535 http://dx.doi.org/10.1038/sj.bjc.6604452

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