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UGT1A1(*)28 genotype and irinotecan dosage in patients with metastatic colorectal cancer: a Dutch Colorectal Cancer Group study

The aim of the study was to investigate the associations between UGT1A1(*)28 genotype and (1) response rates, (2) febrile neutropenia and (3) dose intensity in patients with metastatic colorectal cancer treated with irinotecan. UGT1A1(*)28 genotype was determined in 218 patients receiving irinotecan...

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Detalles Bibliográficos
Autores principales:	Kweekel, D M, Gelderblom, H, Van der Straaten, T, Antonini, N F, Punt, C J A, Guchelaar, H-J
Formato:	Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2008
Materias:	Clinical Study
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2480976/ https://www.ncbi.nlm.nih.gov/pubmed/18594531 http://dx.doi.org/10.1038/sj.bjc.6604461

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