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Adaptive Immune Neuroprotection in G93A-SOD1 Amyotrophic Lateral Sclerosis Mice

BACKGROUND: Innate neuroimmune dysfunction is a pathobiological feature of amyotrophic lateral sclerosis (ALS). However, links, if any, between disease and adaptive immunity are poorly understood. Thus, the role of T cell immunity in disease was investigated in human G93A superoxide dismutase 1 (SOD...

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Detalles Bibliográficos
Autores principales: Banerjee, Rebecca, Mosley, R. Lee, Reynolds, Ashley D., Dhar, Alok, Jackson-Lewis, Vernice, Gordon, Paul H., Przedborski, Serge, Gendelman, Howard E.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2481277/
https://www.ncbi.nlm.nih.gov/pubmed/18648532
http://dx.doi.org/10.1371/journal.pone.0002740