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A Network Model for the Correlation between Epistasis and Genomic Complexity
The study of genetic interactions (epistasis) is central to the understanding of genome organization and evolution. A general correlation between epistasis and genomic complexity has been recently shown, such that in simpler genomes epistasis is antagonistic on average (mutational effects tend to ca...
Autores principales: | Sanjuán, Rafael, Nebot, Miguel R. |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2008
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2481279/ https://www.ncbi.nlm.nih.gov/pubmed/18648534 http://dx.doi.org/10.1371/journal.pone.0002663 |
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