IGF1 Is a Common Target Gene of Ewing's Sarcoma Fusion Proteins in Mesenchymal Progenitor Cells

BACKGROUND: The EWS-FLI-1 fusion protein is associated with 85–90% of Ewing's sarcoma family tumors (ESFT), the remaining 10–15% of cases expressing chimeric genes encoding EWS or FUS fused to one of several ets transcription factor family members, including ERG-1, FEV, ETV1 and ETV6. ESFT are...

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Detalles Bibliográficos
Autores principales: Cironi, Luisa, Riggi, Nicolò, Provero, Paolo, Wolf, Natalie, Suvà, Mario-Luca, Suvà, Domizio, Kindler, Vincent, Stamenkovic, Ivan
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2008
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2481291/
https://www.ncbi.nlm.nih.gov/pubmed/18648544
http://dx.doi.org/10.1371/journal.pone.0002634

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