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Molecular Subsets in the Gene Expression Signatures of Scleroderma Skin

BACKGROUND: Scleroderma is a clinically heterogeneous disease with a complex phenotype. The disease is characterized by vascular dysfunction, tissue fibrosis, internal organ dysfunction, and immune dysfunction resulting in autoantibody production. METHODOLOGY AND FINDINGS: We analyzed the genome-wid...

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Detalles Bibliográficos
Autores principales: Milano, Ausra, Pendergrass, Sarah A., Sargent, Jennifer L., George, Lacy K., McCalmont, Timothy H., Connolly, M. Kari, Whitfield, Michael L.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2481301/
https://www.ncbi.nlm.nih.gov/pubmed/18648520
http://dx.doi.org/10.1371/journal.pone.0002696