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Gene expression response in target organ and whole blood varies as a function of target organ injury phenotype
This report details the standardized experimental design and the different data streams that were collected (histopathology, clinical chemistry, hematology and gene expression from the target tissue (liver) and a bio-available tissue (blood)) after treatment with eight known hepatotoxicants (at mult...
Autores principales: | Lobenhofer, Edward K, Auman, J Todd, Blackshear, Pamela E, Boorman, Gary A, Bushel, Pierre R, Cunningham, Michael L, Fostel, Jennifer M, Gerrish, Kevin, Heinloth, Alexandra N, Irwin, Richard D, Malarkey, David E, Merrick, B Alex, Sieber, Stella O, Tucker, Charles J, Ward, Sandra M, Wilson, Ralph E, Hurban, Patrick, Tennant, Raymond W, Paules, Richard S |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2008
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2481421/ https://www.ncbi.nlm.nih.gov/pubmed/18570634 http://dx.doi.org/10.1186/gb-2008-9-6-r100 |
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