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A mouse plasma peptide atlas as a resource for disease proteomics
We present an in-depth analysis of mouse plasma leading to the development of a publicly available repository composed of 568 liquid chromatography-tandem mass spectrometry runs. A total of 13,779 distinct peptides have been identified with high confidence. The corresponding approximately 3,000 prot...
| Autores principales: | , , , , , , , , , , , , , , , , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2008
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2481425/ https://www.ncbi.nlm.nih.gov/pubmed/18522751 http://dx.doi.org/10.1186/gb-2008-9-6-r93 |
| _version_ | 1782157988506632192 |
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| author | Zhang, Qing Menon, Rajasree Deutsch, Eric W Pitteri, Sharon J Faca, Vitor M Wang, Hong Newcomb, Lisa F DePinho, Ronald A Bardeesy, Nabeel Dinulescu, Daniela Hung, Kenneth E Kucherlapati, Raju Jacks, Tyler Politi, Katerina Aebersold, Ruedi Omenn, Gilbert S States, David J Hanash, Samir M |
| author_facet | Zhang, Qing Menon, Rajasree Deutsch, Eric W Pitteri, Sharon J Faca, Vitor M Wang, Hong Newcomb, Lisa F DePinho, Ronald A Bardeesy, Nabeel Dinulescu, Daniela Hung, Kenneth E Kucherlapati, Raju Jacks, Tyler Politi, Katerina Aebersold, Ruedi Omenn, Gilbert S States, David J Hanash, Samir M |
| author_sort | Zhang, Qing |
| collection | PubMed |
| description | We present an in-depth analysis of mouse plasma leading to the development of a publicly available repository composed of 568 liquid chromatography-tandem mass spectrometry runs. A total of 13,779 distinct peptides have been identified with high confidence. The corresponding approximately 3,000 proteins are estimated to span a 7 logarithmic range of abundance in plasma. A major finding from this study is the identification of novel isoforms and transcript variants not previously predicted from genome analysis. |
| format | Text |
| id | pubmed-2481425 |
| institution | National Center for Biotechnology Information |
| language | English |
| publishDate | 2008 |
| publisher | BioMed Central |
| record_format | MEDLINE/PubMed |
| spelling | pubmed-24814252008-07-24 A mouse plasma peptide atlas as a resource for disease proteomics Zhang, Qing Menon, Rajasree Deutsch, Eric W Pitteri, Sharon J Faca, Vitor M Wang, Hong Newcomb, Lisa F DePinho, Ronald A Bardeesy, Nabeel Dinulescu, Daniela Hung, Kenneth E Kucherlapati, Raju Jacks, Tyler Politi, Katerina Aebersold, Ruedi Omenn, Gilbert S States, David J Hanash, Samir M Genome Biol Method We present an in-depth analysis of mouse plasma leading to the development of a publicly available repository composed of 568 liquid chromatography-tandem mass spectrometry runs. A total of 13,779 distinct peptides have been identified with high confidence. The corresponding approximately 3,000 proteins are estimated to span a 7 logarithmic range of abundance in plasma. A major finding from this study is the identification of novel isoforms and transcript variants not previously predicted from genome analysis. BioMed Central 2008 2008-06-03 /pmc/articles/PMC2481425/ /pubmed/18522751 http://dx.doi.org/10.1186/gb-2008-9-6-r93 Text en Copyright © 2008 Zhang et al.; licensee BioMed Central Ltd. http://creativecommons.org/licenses/by/2.0 This is an open access article distributed under the terms of the Creative Commons Attribution License ( (http://creativecommons.org/licenses/by/2.0) ), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. |
| spellingShingle | Method Zhang, Qing Menon, Rajasree Deutsch, Eric W Pitteri, Sharon J Faca, Vitor M Wang, Hong Newcomb, Lisa F DePinho, Ronald A Bardeesy, Nabeel Dinulescu, Daniela Hung, Kenneth E Kucherlapati, Raju Jacks, Tyler Politi, Katerina Aebersold, Ruedi Omenn, Gilbert S States, David J Hanash, Samir M A mouse plasma peptide atlas as a resource for disease proteomics |
| title | A mouse plasma peptide atlas as a resource for disease proteomics |
| title_full | A mouse plasma peptide atlas as a resource for disease proteomics |
| title_fullStr | A mouse plasma peptide atlas as a resource for disease proteomics |
| title_full_unstemmed | A mouse plasma peptide atlas as a resource for disease proteomics |
| title_short | A mouse plasma peptide atlas as a resource for disease proteomics |
| title_sort | mouse plasma peptide atlas as a resource for disease proteomics |
| topic | Method |
| url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2481425/ https://www.ncbi.nlm.nih.gov/pubmed/18522751 http://dx.doi.org/10.1186/gb-2008-9-6-r93 |
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