Cargando…
Are the so-called low penetrance breast cancer genes, ATM, BRIP1, PALB2 and CHEK2, high risk for women with strong family histories?
A woman typically presents for genetic counselling because she has a strong family history and is interested in knowing the probability she will develop disease in the future; that is, her absolute risk. Relative risk for a given factor refers to risk compared with either population average risk (se...
Autores principales: | Byrnes, Graham B, Southey, Melissa C, Hopper, John L |
---|---|
Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2008
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2481495/ https://www.ncbi.nlm.nih.gov/pubmed/18557994 http://dx.doi.org/10.1186/bcr2099 |
Ejemplares similares
-
PALB2, CHEK2 and ATM rare variants and cancer risk: data from COGS
por: Southey, Melissa C, et al.
Publicado: (2016) -
Incorporating Truncating Variants in PALB2, CHEK2 and ATM into the BOADICEA Breast Cancer Risk Model
por: Lee, Andrew J., et al.
Publicado: (2016) -
Clinical utility of hereditary cancer panel testing: Impact of PALB2, ATM, CHEK2, NBN, BRIP1, RAD51C, and RAD51D results on patient management and adherence to provider recommendations
por: Vysotskaia, Valentina, et al.
Publicado: (2019) -
Rare, protein-truncating variants in ATM, CHEK2 and PALB2, but not XRCC2, are associated with increased breast cancer risks
por: Decker, Brennan, et al.
Publicado: (2017) -
Screening for BRCA1, BRCA2, CHEK2, PALB2, BRIP1, RAD50, and CDH1 mutations in high-risk Finnish BRCA1/2-founder mutation-negative breast and/or ovarian cancer individuals
por: Kuusisto, Kirsi M, et al.
Publicado: (2011)