The effect of tamoxifen on the genital tract

Tamoxifen is a selective estrogen receptor modulator (SERM) that is widely used in the treatment of patients with breast cancer and for chemoprophylaxis in high risk women. Tamoxifen results in a spectrum of abnormalities involving the genital tract, the most significant being an increased incidence...

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Detalles Bibliográficos
Autores principales: Polin, Sandra A., Ascher, Susan M.
Formato: Texto
Lenguaje:English
Publicado: e-Med 2008
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2482152/
https://www.ncbi.nlm.nih.gov/pubmed/18603495
http://dx.doi.org/10.1102/1470-7330.2008.0020
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author Polin, Sandra A.
Ascher, Susan M.
author_facet Polin, Sandra A.
Ascher, Susan M.
author_sort Polin, Sandra A.
collection PubMed
description Tamoxifen is a selective estrogen receptor modulator (SERM) that is widely used in the treatment of patients with breast cancer and for chemoprophylaxis in high risk women. Tamoxifen results in a spectrum of abnormalities involving the genital tract, the most significant being an increased incidence of endometrial cancer and uterine sarcoma. This article reviews the effects of tamoxifen on the genital tract and the strengths and weaknesses of various imaging modalities for evaluating the endometrium.
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spelling pubmed-24821522010-06-30 The effect of tamoxifen on the genital tract Polin, Sandra A. Ascher, Susan M. Cancer Imaging Review Tamoxifen is a selective estrogen receptor modulator (SERM) that is widely used in the treatment of patients with breast cancer and for chemoprophylaxis in high risk women. Tamoxifen results in a spectrum of abnormalities involving the genital tract, the most significant being an increased incidence of endometrial cancer and uterine sarcoma. This article reviews the effects of tamoxifen on the genital tract and the strengths and weaknesses of various imaging modalities for evaluating the endometrium. e-Med 2008-06-30 /pmc/articles/PMC2482152/ /pubmed/18603495 http://dx.doi.org/10.1102/1470-7330.2008.0020 Text en © 2008 International Cancer Imaging Society
spellingShingle Review
Polin, Sandra A.
Ascher, Susan M.
The effect of tamoxifen on the genital tract
title The effect of tamoxifen on the genital tract
title_full The effect of tamoxifen on the genital tract
title_fullStr The effect of tamoxifen on the genital tract
title_full_unstemmed The effect of tamoxifen on the genital tract
title_short The effect of tamoxifen on the genital tract
title_sort effect of tamoxifen on the genital tract
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2482152/
https://www.ncbi.nlm.nih.gov/pubmed/18603495
http://dx.doi.org/10.1102/1470-7330.2008.0020
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