K-ras/PI3K-Akt Signaling Is Essential for Zebrafish Hematopoiesis and Angiogenesis

The RAS small GTPases orchestrate multiple cellular processes. Studies on knock-out mice showed the essential and sufficient role of K-RAS, but not N-RAS and H-RAS in embryonic development. However, many physiological functions of K-RAS in vivo remain unclear. Using wild-type and fli1:GFP transgenic...

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Detalles Bibliográficos
Autores principales: Liu, Lihui, Zhu, Shizhen, Gong, Zhiyuan, Low, Boon Chuan
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2008
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2483249/
https://www.ncbi.nlm.nih.gov/pubmed/18682746
http://dx.doi.org/10.1371/journal.pone.0002850

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