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Characterization of seed nuclei in glucagon aggregation using light scattering methods and field-flow fractionation
BACKGROUND: Glucagon is a peptide hormone with many uses as a therapeutic agent, including the emergency treatment of hypoglycemia. Physical instability of glucagon in solution leads to problems with the manufacture, formulation, and delivery of this pharmaceutical product. Glucagon has been shown t...
Autores principales: | Hoppe, Cindy C, Nguyen, Lida T, Kirsch, Lee E, Wiencek, John M |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2008
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2483260/ https://www.ncbi.nlm.nih.gov/pubmed/18613970 http://dx.doi.org/10.1186/1754-1611-2-10 |
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