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Quantification of mRNA in single cells and modelling of RT-qPCR induced noise
BACKGROUND: Gene expression has a strong stochastic element resulting in highly variable mRNA levels between individual cells, even in a seemingly homogeneous cell population. Access to fundamental information about cellular mechanisms, such as correlated gene expression, motivates measurements of m...
| Autores principales: | , , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2008
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2483285/ https://www.ncbi.nlm.nih.gov/pubmed/18631407 http://dx.doi.org/10.1186/1471-2199-9-63 |