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Voltage Clamp Fluorimetry Reveals a Novel Outer Pore Instability in a Mammalian Voltage-gated Potassium Channel
Voltage-gated potassium (Kv) channel gating involves complex structural rearrangements that regulate the ability of channels to conduct K(+) ions. Fluorescence-based approaches provide a powerful technique to directly report structural dynamics underlying these gating processes in Shaker Kv channels...
Autores principales: | Vaid, Moninder, Claydon, Thomas W., Rezazadeh, Saman, Fedida, David |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
2008
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2483330/ https://www.ncbi.nlm.nih.gov/pubmed/18625849 http://dx.doi.org/10.1085/jgp.200809978 |
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