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Nicotinic Receptor Interloop Proline Anchors β1-β2 and Cys loops in Coupling Agonist Binding to Channel Gating

Nicotinic acetylcholine receptors (AChRs) mediate rapid excitatory synaptic transmission throughout the peripheral and central nervous systems. They transduce binding of nerve-released ACh into opening of an intrinsic channel, yet the structural basis underlying transduction is not fully understood....

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Detalles Bibliográficos
Autores principales:	Lee, Won Yong, Free, Chris R., Sine, Steven M.
Formato:	Texto
Lenguaje:	English
Publicado:	The Rockefeller University Press 2008
Materias:	Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2483337/ https://www.ncbi.nlm.nih.gov/pubmed/18663134 http://dx.doi.org/10.1085/jgp.200810014

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