Boc5, a Non-Peptidic Glucagon-Like Peptide-1 Receptor Agonist, Invokes Sustained Glycemic Control and Weight Loss in Diabetic Mice

BACKGROUND: Our recent discovery of the substituted cyclobutane Boc5, one of the first non-peptidic agonists at glucagon-like peptide-1 receptors, offers the potential of combining oral availability with full agonism capable of eliciting antidiabetic and antiobesity effects. The present study was ai...

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Detalles Bibliográficos
Autores principales: Su, Haoran, He, Min, Li, Hongmei, Liu, Qing, Wang, Jia, Wang, Yiqian, Gao, Weiwei, Zhou, Ling, Liao, Jiayu, Young, Andrew A., Wang, Ming-Wei
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2008
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2483413/
https://www.ncbi.nlm.nih.gov/pubmed/18682834
http://dx.doi.org/10.1371/journal.pone.0002892

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