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Disruption of Neuronal Autophagy by Infected Microglia Results in Neurodegeneration

There is compelling evidence to support the idea that autophagy has a protective function in neurons and its disruption results in neurodegenerative disorders. Neuronal damage is well-documented in the brains of HIV-infected individuals, and evidence of inflammation, oxidative stress, damage to syna...

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Detalles Bibliográficos
Autores principales: Alirezaei, Mehrdad, Kiosses, William B., Flynn, Claudia T., Brady, Nathan R., Fox, Howard S.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2483417/
https://www.ncbi.nlm.nih.gov/pubmed/18682838
http://dx.doi.org/10.1371/journal.pone.0002906

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