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Disruption of Neuronal Autophagy by Infected Microglia Results in Neurodegeneration
There is compelling evidence to support the idea that autophagy has a protective function in neurons and its disruption results in neurodegenerative disorders. Neuronal damage is well-documented in the brains of HIV-infected individuals, and evidence of inflammation, oxidative stress, damage to syna...
Autores principales: | Alirezaei, Mehrdad, Kiosses, William B., Flynn, Claudia T., Brady, Nathan R., Fox, Howard S. |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2008
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2483417/ https://www.ncbi.nlm.nih.gov/pubmed/18682838 http://dx.doi.org/10.1371/journal.pone.0002906 |
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