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High mobility group box-1 protein as a tumor necrosis factor-independent therapeutic target in rheumatoid arthritis
Rheumatoid arthritis (RA) remains a prevalent disease worldwide that causes significant morbidity and mortality despite recent therapeutics. High mobility group box-1 (HMGB1) protein, originally appreciated as an intranuclear DNA binding protein, has been implicated as an integral mediator in the pa...
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| Formato: | Texto |
| Lenguaje: | English |
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BioMed Central
2008
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2483447/ https://www.ncbi.nlm.nih.gov/pubmed/18557992 http://dx.doi.org/10.1186/ar2427 |