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Cartilage degradation is fully reversible in the presence of aggrecanase but not matrix metalloproteinase activity

INTRODUCTION: Physiological and pathophysiological cartilage turnover may coexist in articular cartilage. The distinct enzymatic processes leading to irreversible cartilage damage, compared with those needed for continuous self-repair and regeneration, remain to be identified. We investigated the ca...

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Detalles Bibliográficos
Autores principales: Karsdal, Morten A, Madsen, Suzi H, Christiansen, Claus, Henriksen, Kim, Fosang, Amanda J, Sondergaard, Bodil C
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2483454/
https://www.ncbi.nlm.nih.gov/pubmed/18513402
http://dx.doi.org/10.1186/ar2434