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Cartilage degradation is fully reversible in the presence of aggrecanase but not matrix metalloproteinase activity
INTRODUCTION: Physiological and pathophysiological cartilage turnover may coexist in articular cartilage. The distinct enzymatic processes leading to irreversible cartilage damage, compared with those needed for continuous self-repair and regeneration, remain to be identified. We investigated the ca...
Autores principales: | Karsdal, Morten A, Madsen, Suzi H, Christiansen, Claus, Henriksen, Kim, Fosang, Amanda J, Sondergaard, Bodil C |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2008
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2483454/ https://www.ncbi.nlm.nih.gov/pubmed/18513402 http://dx.doi.org/10.1186/ar2434 |
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