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Crystallization of protein–ligand complexes

Obtaining diffraction-quality crystals has long been a bottleneck in solving the three-dimensional structures of proteins. Often proteins may be stabilized when they are complexed with a substrate, nucleic acid, cofactor or small molecule. These ligands, on the other hand, have the potential to indu...

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Detalles Bibliográficos
Autores principales: Hassell, Anne M., An, Gang, Bledsoe, Randy K., Bynum, Jane M., Carter, H. Luke, Deng, Su-Jun J., Gampe, Robert T., Grisard, Tamara E., Madauss, Kevin P., Nolte, Robert T., Rocque, Warren J., Wang, Liping, Weaver, Kurt L., Williams, Shawn P., Wisely, G. Bruce, Xu, Robert, Shewchuk, Lisa M.
Formato: Texto
Lenguaje:English
Publicado: International Union of Crystallography 2007
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2483499/
https://www.ncbi.nlm.nih.gov/pubmed/17164529
http://dx.doi.org/10.1107/S0907444906047020

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