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Crystallization of protein–ligand complexes
Obtaining diffraction-quality crystals has long been a bottleneck in solving the three-dimensional structures of proteins. Often proteins may be stabilized when they are complexed with a substrate, nucleic acid, cofactor or small molecule. These ligands, on the other hand, have the potential to indu...
Autores principales: | Hassell, Anne M., An, Gang, Bledsoe, Randy K., Bynum, Jane M., Carter, H. Luke, Deng, Su-Jun J., Gampe, Robert T., Grisard, Tamara E., Madauss, Kevin P., Nolte, Robert T., Rocque, Warren J., Wang, Liping, Weaver, Kurt L., Williams, Shawn P., Wisely, G. Bruce, Xu, Robert, Shewchuk, Lisa M. |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
International Union of Crystallography
2007
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2483499/ https://www.ncbi.nlm.nih.gov/pubmed/17164529 http://dx.doi.org/10.1107/S0907444906047020 |
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