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Spindle checkpoint activation at meiosis I advances anaphase II onset via meiosis-specific APC/C regulation

During mitosis, the spindle assembly checkpoint (SAC) inhibits the Cdc20-activated anaphase-promoting complex/cyclosome (APC/C(Cdc20)), which promotes protein degradation, and delays anaphase onset to ensure accurate chromosome segregation. However, the SAC function in meiotic anaphase regulation is...

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Detalles Bibliográficos
Autores principales:	Yamamoto, Ayumu, Kitamura, Kenji, Hihara, Daisuke, Hirose, Yukinobu, Katsuyama, Satoshi, Hiraoka, Yasushi
Formato:	Texto
Lenguaje:	English
Publicado:	The Rockefeller University Press 2008
Materias:	Research Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2483520/ https://www.ncbi.nlm.nih.gov/pubmed/18644893 http://dx.doi.org/10.1083/jcb.200802053

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