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The concept of translocational regulation
Biological processes are regulated to provide cells with exquisite adaptability to changing environmental conditions and cellular demands. The mechanisms regulating secretory and membrane protein translocation into the endoplasmic reticulum (ER) are unknown. A conceptual framework for translocationa...
Autores principales: | , |
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Formato: | Texto |
Lenguaje: | English |
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The Rockefeller University Press
2008
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2483521/ https://www.ncbi.nlm.nih.gov/pubmed/18644895 http://dx.doi.org/10.1083/jcb.200804157 |
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author | Hegde, Ramanujan S. Kang, Sang-Wook |
author_facet | Hegde, Ramanujan S. Kang, Sang-Wook |
author_sort | Hegde, Ramanujan S. |
collection | PubMed |
description | Biological processes are regulated to provide cells with exquisite adaptability to changing environmental conditions and cellular demands. The mechanisms regulating secretory and membrane protein translocation into the endoplasmic reticulum (ER) are unknown. A conceptual framework for translocational regulation is proposed based on our current mechanistic understanding of ER protein translocation and general principles of regulatory control. |
format | Text |
id | pubmed-2483521 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2008 |
publisher | The Rockefeller University Press |
record_format | MEDLINE/PubMed |
spelling | pubmed-24835212009-01-28 The concept of translocational regulation Hegde, Ramanujan S. Kang, Sang-Wook J Cell Biol Reviews Biological processes are regulated to provide cells with exquisite adaptability to changing environmental conditions and cellular demands. The mechanisms regulating secretory and membrane protein translocation into the endoplasmic reticulum (ER) are unknown. A conceptual framework for translocational regulation is proposed based on our current mechanistic understanding of ER protein translocation and general principles of regulatory control. The Rockefeller University Press 2008-07-28 /pmc/articles/PMC2483521/ /pubmed/18644895 http://dx.doi.org/10.1083/jcb.200804157 Text en Copyright © 2008, The Rockefeller University Press https://creativecommons.org/licenses/by-nc-sa/4.0/This article is distributed under a Creative Commons License (Attribution–Noncommercial–Share Alike 4.0 International license, as described at https://creativecommons.org/licenses/by-nc-sa/4.0/). |
spellingShingle | Reviews Hegde, Ramanujan S. Kang, Sang-Wook The concept of translocational regulation |
title | The concept of translocational regulation |
title_full | The concept of translocational regulation |
title_fullStr | The concept of translocational regulation |
title_full_unstemmed | The concept of translocational regulation |
title_short | The concept of translocational regulation |
title_sort | concept of translocational regulation |
topic | Reviews |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2483521/ https://www.ncbi.nlm.nih.gov/pubmed/18644895 http://dx.doi.org/10.1083/jcb.200804157 |
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