Building a spindle of the correct length in human cells requires the interaction between TPX2 and Aurora A

To assemble mitotic spindles, cells nucleate microtubules from a variety of sources including chromosomes and centrosomes. We know little about how the regulation of microtubule nucleation contributes to spindle bipolarity and spindle size. The Aurora A kinase activator TPX2 is required for microtub...

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Detalles Bibliográficos
Autores principales: Bird, Alexander W., Hyman, Anthony A.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2008
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2483532/
https://www.ncbi.nlm.nih.gov/pubmed/18663142
http://dx.doi.org/10.1083/jcb.200802005

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2483532/
https://www.ncbi.nlm.nih.gov/pubmed/18663142
http://dx.doi.org/10.1083/jcb.200802005

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