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Building a spindle of the correct length in human cells requires the interaction between TPX2 and Aurora A
To assemble mitotic spindles, cells nucleate microtubules from a variety of sources including chromosomes and centrosomes. We know little about how the regulation of microtubule nucleation contributes to spindle bipolarity and spindle size. The Aurora A kinase activator TPX2 is required for microtub...
| Autores principales: | , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
The Rockefeller University Press
2008
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2483532/ https://www.ncbi.nlm.nih.gov/pubmed/18663142 http://dx.doi.org/10.1083/jcb.200802005 |