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Mathematical Analysis of Copy Number Variation in a DNA Sample Using Digital PCR on a Nanofluidic Device

Copy Number Variations (CNVs) of regions of the human genome have been associated with multiple diseases. We present an algorithm which is mathematically sound and computationally efficient to accurately analyze CNV in a DNA sample utilizing a nanofluidic device, known as the digital array. This num...

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Detalles Bibliográficos
Autores principales: Dube, Simant, Qin, Jian, Ramakrishnan, Ramesh
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2483940/
https://www.ncbi.nlm.nih.gov/pubmed/18682853
http://dx.doi.org/10.1371/journal.pone.0002876

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