Off-Target Effects of Psychoactive Drugs Revealed by Genome-Wide Assays in Yeast

To better understand off-target effects of widely prescribed psychoactive drugs, we performed a comprehensive series of chemogenomic screens using the budding yeast Saccharomyces cerevisiae as a model system. Because the known human targets of these drugs do not exist in yeast, we could employ the y...

Descripción completa

Detalles Bibliográficos
Autores principales: Ericson, Elke, Gebbia, Marinella, Heisler, Lawrence E., Wildenhain, Jan, Tyers, Mike, Giaever, Guri, Nislow, Corey
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2008
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2483942/
https://www.ncbi.nlm.nih.gov/pubmed/18688276
http://dx.doi.org/10.1371/journal.pgen.1000151

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2483942/
https://www.ncbi.nlm.nih.gov/pubmed/18688276
http://dx.doi.org/10.1371/journal.pgen.1000151

Ejemplares similares