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Off-Target Effects of Psychoactive Drugs Revealed by Genome-Wide Assays in Yeast
To better understand off-target effects of widely prescribed psychoactive drugs, we performed a comprehensive series of chemogenomic screens using the budding yeast Saccharomyces cerevisiae as a model system. Because the known human targets of these drugs do not exist in yeast, we could employ the y...
Autores principales: | Ericson, Elke, Gebbia, Marinella, Heisler, Lawrence E., Wildenhain, Jan, Tyers, Mike, Giaever, Guri, Nislow, Corey |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2008
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2483942/ https://www.ncbi.nlm.nih.gov/pubmed/18688276 http://dx.doi.org/10.1371/journal.pgen.1000151 |
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