Cargando…

Genetic Evidence of Serum Phosphate-Independent Functions of FGF-23 on Bone

Maintenance of physiologic phosphate balance is of crucial biological importance, as it is fundamental to cellular function, energy metabolism, and skeletal mineralization. Fibroblast growth factor-23 (FGF-23) is a master regulator of phosphate homeostasis, but the molecular mechanism of such regula...

Descripción completa

Detalles Bibliográficos
Autores principales:	Sitara, Despina, Kim, Somi, Razzaque, Mohammed S., Bergwitz, Clemens, Taguchi, Takashi, Schüler, Christiane, Erben, Reinhold G., Lanske, Beate
Formato:	Texto
Lenguaje:	English
Publicado:	Public Library of Science 2008
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2483943/ https://www.ncbi.nlm.nih.gov/pubmed/18688277 http://dx.doi.org/10.1371/journal.pgen.1000154

Ejemplares similares

Molecular interactions of FGF23 and PTH in phosphate regulation
por: Lanske, Beate, et al.
Publicado: (2014)

Pleiotropic Actions of FGF23
por: Erben, Reinhold G.
Publicado: (2017)

FGF23 regulates renal sodium handling and blood pressure
por: Andrukhova, Olena, et al.
Publicado: (2014)

FGF23 and Vitamin D Metabolism
por: Latic, Nejla, et al.
Publicado: (2021)

FGF23 acts directly on renal proximal tubules to induce phosphaturia through activation of the ERK1/2–SGK1 signaling pathway
por: Andrukhova, Olena, et al.
Publicado: (2012)

FGF23 neutralization improves bone quality and osseointegration of titanium implants in chronic kidney disease mice
por: Sun, Ningyuan, et al.
Publicado: (2015)

Editorial: Endocrine and Paracrine Role of FGF23 and Klotho in Health and Disease
por: Erben, Reinhold G.
Publicado: (2019)

FGF23 promotes renal calcium reabsorption through the TRPV5 channel
por: Andrukhova, Olena, et al.
Publicado: (2014)

Interactions between FGF23 and vitamin D
por: Razzaque, Mohammed S
Publicado: (2022)

Phosphate and FGF-23
por: Jüppner, Harald
Publicado: (2011)

FGF-23–Klotho signaling stimulates proliferation and prevents vitamin D–induced apoptosis
por: Medici, Damian, et al.
Publicado: (2008)

Aldosterone Is Positively Associated With Circulating FGF23 Levels in Chronic Kidney Disease Across Four Species, and May Drive FGF23 Secretion Directly
por: Radloff, Judith, et al.
Publicado: (2021)

Interaction of Vitamin D with Peptide Hormones with Emphasis on Parathyroid Hormone, FGF23, and the Renin-Angiotensin-Aldosterone System
por: Latic, Nejla, et al.
Publicado: (2022)

LBSUN132 Adipocyte-specific Ablation Of Fgf23 Attenuates Diet-induced Obesity In Female Mice
por: Park, Min Young, et al.
Publicado: (2022)

Renal Phosphate Handling: Independent Effects of Circulating FGF23, PTH, and Calcium
por: McKenna, Malachi J, et al.
Publicado: (2020)

C-FGF23 peptide alleviates hypoferremia during acute inflammation
por: Agoro, Rafiou, et al.
Publicado: (2020)

Deletion of PTH Rescues Skeletal Abnormalities and High Osteopontin Levels in Klotho (−/−) Mice
por: Yuan, Quan, et al.
Publicado: (2012)

FGF23 and Phosphate–Cardiovascular Toxins in CKD
por: Vogt, Isabel, et al.
Publicado: (2019)

Excessive Osteocytic Fgf23 Secretion Contributes to Pyrophosphate Accumulation and Mineralization Defect in Hyp Mice
por: Murali, Sathish K., et al.
Publicado: (2016)

Fibroblast Growth Factor 23 (FGF23) and Disorders of Phosphate Metabolism
por: Saito, Tasuku, et al.
Publicado: (2009)

Augmented Fibroblast Growth Factor-23 Secretion in Bone Locally Contributes to Impaired Bone Mineralization in Chronic Kidney Disease in Mice
por: Andrukhova, Olena, et al.
Publicado: (2018)

Skeletal FGFR1 signaling is necessary for regulation of serum phosphate level by FGF23 and normal life span
por: Takashi, Yuichi, et al.
Publicado: (2021)

Intact FGF23 predicts serum phosphate improvement after combined nicotinamide and phosphate binder treatment in hemodialysis patients
por: Egli-Spichtig, Daniela, et al.
Publicado: (2023)

Serum Phosphate Levels Modify the Impact of FGF23 Levels on Hemoglobin in Chronic Kidney Disease
por: Navarro-González, Juan F., et al.
Publicado: (2022)

Activation of unliganded FGF receptor by extracellular phosphate potentiates proteolytic protection of FGF23 by its O-glycosylation
por: Takashi, Yuichi, et al.
Publicado: (2019)

Phosphate control in reducing FGF23 levels in hemodialysis patients
por: Rodelo-Haad, Cristian, et al.
Publicado: (2018)

Genetic Ablation of Fgf23 or Klotho Does not Modulate Experimental Heart Hypertrophy Induced by Pressure Overload
por: Slavic, Svetlana, et al.
Publicado: (2017)

Variation in the fibroblast growth factor 23 (FGF23) gene associates with serum FGF23 and bone strength in infants
por: Enlund-Cerullo, Maria, et al.
Publicado: (2023)

FGF-23: More Than a Regulator of Renal Phosphate Handling?
por: Jüppner, Harald, et al.
Publicado: (2010)

Physiological Actions of Fibroblast Growth Factor-23
por: Erben, Reinhold G.
Publicado: (2018)

Associations of Calcium from Food Sources versus Phosphate Binders with Serum Calcium and FGF23 in Hemodialysis Patients
por: Mahdavi, Sara, et al.
Publicado: (2019)

FGF23 Deficiency Leads to Mixed Hearing Loss and Middle Ear Malformation in Mice
por: Lysaght, Andrew C., et al.
Publicado: (2014)

FGF-23 and sclerostin in serum and bone of CKD patients
por: Lima, Florence, et al.
Publicado: (2023)

Impact of fractional phosphate excretion on the relation of FGF23 with outcome in CKD patients
por: Bech, Anneke P., et al.
Publicado: (2015)

Interaction between serum FGF-23 and PTH in renal phosphate excretion, a case-control study in hypoparathyroid patients
por: Saki, Forough, et al.
Publicado: (2020)

α-Klotho's effects on mineral homeostasis are fibroblast growth factor-23 dependent
por: Erben, Reinhold G.
Publicado: (2018)

Serum FGF23 levels may not be associated with serum phosphate and 1,25-dihydroxyvitamin D levels in patients with Fanconi syndrome–induced hypophosphatemia
por: Goto, Shunsuke, et al.
Publicado: (2016)

Infigratinib Reduces Fibroblast Growth Factor 23 (FGF23) and Increases Blood Phosphate in Tumor‐Induced Osteomalacia
por: Hartley, Iris R., et al.
Publicado: (2022)

Central role of the proximal tubular αKlotho/FGF receptor complex in FGF23-regulated phosphate and vitamin D metabolism
por: Takeshita, Ai, et al.
Publicado: (2018)

Intra-articularly injected mesenchymal stem cells promote cartilage regeneration, but do not permanently engraft in distant organs
por: Satué, María, et al.
Publicado: (2019)

Cannot write session to /tmp/vufind_sessions/sess_2tp5cf25t7l9fa5bkubttf1sa8