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Characterization of a Lipoyl Domain-independent B-cell Autoepitope on the Human Branched-chain Acyltransferase in Primary Biliary Cirrhosis and Overlap Syndrome with Autoimmune Hepatitis

Background and aims: Antimitochondrial antibodies (AMA) which recognize pyruvate acetyltransferase (PDC-E2) represent a highly diagnostic feature of primary biliary cirrhosis (PBC). The analysis of immunofluorescence (IF)-AMA-positive sera in PBC patients indicates a conformational epitope located w...

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Detalles Bibliográficos
Autores principales:	Csepregi, Antal, Obermayer-Straub, Petra, Kneip, Susanne, Kayser, Anne, Loges, Stephanie, Schmidt, Eleonore, Nemesánszky, Elemér, Szalay, Ferenc, Manns, Michael P., Strassburg, Christian P.
Formato:	Texto
Lenguaje:	English
Publicado:	Hindawi Publishing Corporation 2003
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2485412/ https://www.ncbi.nlm.nih.gov/pubmed/14768949 http://dx.doi.org/10.1080/10446670310001642159

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