Antigenic Variation in Trypanosoma brucei: Joining the DOTs

The survival ofTrypanosoma brucei relies on the sucessive expression of a single surface protein gene from a family of around 1,000 genes. This switching appears to be partly dictated by epigenetic changes in chromatin.

Detalles Bibliográficos
Autores principales: Stockdale, Chris, Swiderski, Michal R, Barry, J. David, McCulloch, Richard
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2008
Materias:
Primer
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2486309/
https://www.ncbi.nlm.nih.gov/pubmed/18666832
http://dx.doi.org/10.1371/journal.pbio.0060185
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author Stockdale, Chris
Swiderski, Michal R
Barry, J. David
McCulloch, Richard
author_facet Stockdale, Chris
Swiderski, Michal R
Barry, J. David
McCulloch, Richard
author_sort Stockdale, Chris
collection PubMed
description The survival ofTrypanosoma brucei relies on the sucessive expression of a single surface protein gene from a family of around 1,000 genes. This switching appears to be partly dictated by epigenetic changes in chromatin.
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spelling pubmed-24863092008-07-26 Antigenic Variation in Trypanosoma brucei: Joining the DOTs Stockdale, Chris Swiderski, Michal R Barry, J. David McCulloch, Richard PLoS Biol Primer The survival ofTrypanosoma brucei relies on the sucessive expression of a single surface protein gene from a family of around 1,000 genes. This switching appears to be partly dictated by epigenetic changes in chromatin. Public Library of Science 2008-07 2008-07-29 /pmc/articles/PMC2486309/ /pubmed/18666832 http://dx.doi.org/10.1371/journal.pbio.0060185 Text en © 2008 Stockdale et al. http://creativecommons.org/licenses/by/4.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are properly credited.
spellingShingle Primer
Stockdale, Chris
Swiderski, Michal R
Barry, J. David
McCulloch, Richard
Antigenic Variation in Trypanosoma brucei: Joining the DOTs
title Antigenic Variation in Trypanosoma brucei: Joining the DOTs
title_full Antigenic Variation in Trypanosoma brucei: Joining the DOTs
title_fullStr Antigenic Variation in Trypanosoma brucei: Joining the DOTs
title_full_unstemmed Antigenic Variation in Trypanosoma brucei: Joining the DOTs
title_short Antigenic Variation in Trypanosoma brucei: Joining the DOTs
title_sort antigenic variation in trypanosoma brucei: joining the dots
topic Primer
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2486309/
https://www.ncbi.nlm.nih.gov/pubmed/18666832
http://dx.doi.org/10.1371/journal.pbio.0060185
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AT barryjdavid antigenicvariationintrypanosomabruceijoiningthedots
AT mccullochrichard antigenicvariationintrypanosomabruceijoiningthedots

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