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Oscillating Per-Cision
In a similar manner to humans, fly circadian clock proteins are regulated by multiple phosphorylation sites, which affect a protein's activity or stability. A suicide model for destruction of transcriptional machinery may explain a conserved mechanism that gives the circadian clock a chance to...
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2008
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2486315/ https://www.ncbi.nlm.nih.gov/pubmed/18666835 http://dx.doi.org/10.1371/journal.pbio.0060192 |
Sumario: | In a similar manner to humans, fly circadian clock proteins are regulated by multiple phosphorylation sites, which affect a protein's activity or stability. A suicide model for destruction of transcriptional machinery may explain a conserved mechanism that gives the circadian clock a chance to respond to varying cellular influences throughout the circadian day. |
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