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The Threat of Instability: Neurodegeneration Predicted by Protein Destabilization and Aggregation Propensity
A new method based on protein stability and aggregation propensity reveals a strong correlation between the properties of mutant Cu/Zn-superoxide dismutases associated with amyotrophic lateral sclerosis and patient survival.
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| Formato: | Texto |
| Lenguaje: | English |
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Public Library of Science
2008
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2486316/ https://www.ncbi.nlm.nih.gov/pubmed/18666836 http://dx.doi.org/10.1371/journal.pbio.0060193 |