On the Mechanisms of the Protective Effect of Infections on Type 1 Diabetes

The incidence of type 1 diabetes (T1D) shows a worrying tendency for a steady increase in Western countries. Along the line of the hygiene hypothesis, evidence accumulates to suggest that this increase is explained by the decrease of infections due to improved hygiene and medical care. This article...

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Detalles Bibliográficos
Autores principales: Feillet, Hélène, Bach, Jean-François
Formato: Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2004
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2486326/
https://www.ncbi.nlm.nih.gov/pubmed/15559363
http://dx.doi.org/10.1080/17402520400004557
Descripción
Sumario:The incidence of type 1 diabetes (T1D) shows a worrying tendency for a steady increase in Western countries. Along the line of the hygiene hypothesis, evidence accumulates to suggest that this increase is explained by the decrease of infections due to improved hygiene and medical care. This article presents a review of epidemiological data and of the main putative underlying cellular and molecular mechanisms.

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