On the Mechanisms of the Protective Effect of Infections on Type 1 Diabetes

The incidence of type 1 diabetes (T1D) shows a worrying tendency for a steady increase in Western countries. Along the line of the hygiene hypothesis, evidence accumulates to suggest that this increase is explained by the decrease of infections due to improved hygiene and medical care. This article...

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Detalles Bibliográficos
Autores principales: Feillet, Hélène, Bach, Jean-François
Formato: Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2004
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2486326/
https://www.ncbi.nlm.nih.gov/pubmed/15559363
http://dx.doi.org/10.1080/17402520400004557
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author Feillet, Hélène
Bach, Jean-François
author_facet Feillet, Hélène
Bach, Jean-François
author_sort Feillet, Hélène
collection PubMed
description The incidence of type 1 diabetes (T1D) shows a worrying tendency for a steady increase in Western countries. Along the line of the hygiene hypothesis, evidence accumulates to suggest that this increase is explained by the decrease of infections due to improved hygiene and medical care. This article presents a review of epidemiological data and of the main putative underlying cellular and molecular mechanisms.
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spelling pubmed-24863262008-07-26 On the Mechanisms of the Protective Effect of Infections on Type 1 Diabetes Feillet, Hélène Bach, Jean-François Clin Dev Immunol Research Article The incidence of type 1 diabetes (T1D) shows a worrying tendency for a steady increase in Western countries. Along the line of the hygiene hypothesis, evidence accumulates to suggest that this increase is explained by the decrease of infections due to improved hygiene and medical care. This article presents a review of epidemiological data and of the main putative underlying cellular and molecular mechanisms. Hindawi Publishing Corporation 2004 /pmc/articles/PMC2486326/ /pubmed/15559363 http://dx.doi.org/10.1080/17402520400004557 Text en Copyright © 2004 Hindawi Publishing Corporation. http://creativecommons.org/licenses/by/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Research Article
Feillet, Hélène
Bach, Jean-François
On the Mechanisms of the Protective Effect of Infections on Type 1 Diabetes
title On the Mechanisms of the Protective Effect of Infections on Type 1 Diabetes
title_full On the Mechanisms of the Protective Effect of Infections on Type 1 Diabetes
title_fullStr On the Mechanisms of the Protective Effect of Infections on Type 1 Diabetes
title_full_unstemmed On the Mechanisms of the Protective Effect of Infections on Type 1 Diabetes
title_short On the Mechanisms of the Protective Effect of Infections on Type 1 Diabetes
title_sort on the mechanisms of the protective effect of infections on type 1 diabetes
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2486326/
https://www.ncbi.nlm.nih.gov/pubmed/15559363
http://dx.doi.org/10.1080/17402520400004557
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