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Trifluoromethyl ethers – synthesis and properties of an unusual substituent
After nitrogen, fluorine is probably the next most favorite hetero-atom for incorporation into small molecules in life science-oriented research. This review focuses on a particular fluorinated substituent, the trifluoromethoxy group, which is finding increased utility as a substituent in bioactives...
Autores principales: | Leroux, Frédéric R, Manteau, Baptiste, Vors, Jean-Pierre, Pazenok, Sergiy |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Beilstein-Institut
2008
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2486484/ https://www.ncbi.nlm.nih.gov/pubmed/18941485 http://dx.doi.org/10.3762/bjoc.4.13 |
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