New acylides: synthesis of 3-O-[γ-(4-oxo-2-aryl-thiazolidin-3-yl)butyryl]erythromycin A derivatives

In search of new erythromycin derivatives 3-O-[γ-(4-oxo-2-aryl-thiazolidin-3-yl)butyryl]erythromycin A derivatives have been synthesized. The 3-hydroxy group was derivatised to a primary amine and subsequently the thiazolidinone nucleus was generated at the amino functionality through DCC mediated o...

Descripción completa

Detalles Bibliográficos
Autores principales: Pandey, Deepa, Haq, Wahajul, Katti, Seturam B
Formato: Texto
Lenguaje:English
Publicado: Beilstein-Institut 2008
Materias:
Full Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2486485/
https://www.ncbi.nlm.nih.gov/pubmed/18941486
http://dx.doi.org/10.3762/bjoc.4.14
_version_ 1782158109340336128
author Pandey, Deepa
Haq, Wahajul
Katti, Seturam B
author_facet Pandey, Deepa
Haq, Wahajul
Katti, Seturam B
author_sort Pandey, Deepa
collection PubMed
description In search of new erythromycin derivatives 3-O-[γ-(4-oxo-2-aryl-thiazolidin-3-yl)butyryl]erythromycin A derivatives have been synthesized. The 3-hydroxy group was derivatised to a primary amine and subsequently the thiazolidinone nucleus was generated at the amino functionality through DCC mediated one-pot three-component reaction in good yields.
format Text
id pubmed-2486485
institution National Center for Biotechnology Information
language English
publishDate 2008
publisher Beilstein-Institut
record_format MEDLINE/PubMed
spelling pubmed-24864852008-10-20 New acylides: synthesis of 3-O-[γ-(4-oxo-2-aryl-thiazolidin-3-yl)butyryl]erythromycin A derivatives Pandey, Deepa Haq, Wahajul Katti, Seturam B Beilstein J Org Chem Full Research Paper In search of new erythromycin derivatives 3-O-[γ-(4-oxo-2-aryl-thiazolidin-3-yl)butyryl]erythromycin A derivatives have been synthesized. The 3-hydroxy group was derivatised to a primary amine and subsequently the thiazolidinone nucleus was generated at the amino functionality through DCC mediated one-pot three-component reaction in good yields. Beilstein-Institut 2008-05-13 /pmc/articles/PMC2486485/ /pubmed/18941486 http://dx.doi.org/10.3762/bjoc.4.14 Text en Copyright © 2008, Pandey et al. https://creativecommons.org/licenses/by/2.0https://www.beilstein-journals.org/bjoc/termsThis is an Open Access article under the terms of the Creative Commons Attribution License (https://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. The license is subject to the Beilstein Journal of Organic Chemistry terms and conditions: (https://www.beilstein-journals.org/bjoc/terms)
spellingShingle Full Research Paper
Pandey, Deepa
Haq, Wahajul
Katti, Seturam B
New acylides: synthesis of 3-O-[γ-(4-oxo-2-aryl-thiazolidin-3-yl)butyryl]erythromycin A derivatives
title New acylides: synthesis of 3-O-[γ-(4-oxo-2-aryl-thiazolidin-3-yl)butyryl]erythromycin A derivatives
title_full New acylides: synthesis of 3-O-[γ-(4-oxo-2-aryl-thiazolidin-3-yl)butyryl]erythromycin A derivatives
title_fullStr New acylides: synthesis of 3-O-[γ-(4-oxo-2-aryl-thiazolidin-3-yl)butyryl]erythromycin A derivatives
title_full_unstemmed New acylides: synthesis of 3-O-[γ-(4-oxo-2-aryl-thiazolidin-3-yl)butyryl]erythromycin A derivatives
title_short New acylides: synthesis of 3-O-[γ-(4-oxo-2-aryl-thiazolidin-3-yl)butyryl]erythromycin A derivatives
title_sort new acylides: synthesis of 3-o-[γ-(4-oxo-2-aryl-thiazolidin-3-yl)butyryl]erythromycin a derivatives
topic Full Research Paper
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2486485/
https://www.ncbi.nlm.nih.gov/pubmed/18941486
http://dx.doi.org/10.3762/bjoc.4.14
work_keys_str_mv AT pandeydeepa newacylidessynthesisof3og4oxo2arylthiazolidin3ylbutyrylerythromycinaderivatives
AT haqwahajul newacylidessynthesisof3og4oxo2arylthiazolidin3ylbutyrylerythromycinaderivatives
AT kattiseturamb newacylidessynthesisof3og4oxo2arylthiazolidin3ylbutyrylerythromycinaderivatives

Ejemplares similares