Minority HIV-1 Drug Resistance Mutations Are Present in Antiretroviral Treatment–Naïve Populations and Associate with Reduced Treatment Efficacy

BACKGROUND: Transmitted HIV-1 drug resistance can compromise initial antiretroviral therapy (ART); therefore, its detection is important for patient management. The absence of drug-associated selection pressure in treatment-naïve persons can cause drug-resistant viruses to decline to levels undetect...

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Detalles Bibliográficos
Autores principales: Johnson, Jeffrey A, Li, Jin-Fen, Wei, Xierong, Lipscomb, Jonathan, Irlbeck, David, Craig, Charles, Smith, Amanda, Bennett, Diane E, Monsour, Michael, Sandstrom, Paul, Lanier, E. Randall, Heneine, Walid
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2008
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2488194/
https://www.ncbi.nlm.nih.gov/pubmed/18666824
http://dx.doi.org/10.1371/journal.pmed.0050158

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