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Regional variations in Paneth cell antimicrobial peptide expression along the mouse intestinal tract

BACKGROUND: Enteric antimicrobial peptides secreted from Paneth cells, including α-defensins (in mice named cryptdins), are key effector molecules of innate immunity in the small intestine. The importance of Paneth cells α-defensins emerged from studies of enteric bacterial infection in genetically...

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Detalles Bibliográficos
Autores principales: Karlsson, Jenny, Pütsep, Katrin, Chu, Hiutung, Kays, Robert J, Bevins, Charles L, Andersson, Mats
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2488317/
https://www.ncbi.nlm.nih.gov/pubmed/18637162
http://dx.doi.org/10.1186/1471-2172-9-37