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Regional variations in Paneth cell antimicrobial peptide expression along the mouse intestinal tract
BACKGROUND: Enteric antimicrobial peptides secreted from Paneth cells, including α-defensins (in mice named cryptdins), are key effector molecules of innate immunity in the small intestine. The importance of Paneth cells α-defensins emerged from studies of enteric bacterial infection in genetically...
Autores principales: | , , , , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2008
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2488317/ https://www.ncbi.nlm.nih.gov/pubmed/18637162 http://dx.doi.org/10.1186/1471-2172-9-37 |