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Metastatic susceptibility locus, an 8p hot-spot for tumour progression disrupted in colorectal liver metastases: 13 candidate genes examined at the DNA, mRNA and protein level

BACKGROUND: Mortality from colorectal cancer is mainly due to metastatic liver disease. Improved understanding of the molecular events underlying metastasis is crucial for the development of new methods for early detection and treatment of colorectal cancer. Loss of chromosome 8p is frequently seen...

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Detalles Bibliográficos
Autores principales: Macartney-Coxson, Donia P, Hood, Kylie A, Shi, Hong-jun, Ward, Teresa, Wiles, Anna, O'Connor, Rosemary, Hall, David A, Lea, Rod A, Royds, Janice A, Stubbs, Richard S, Rooker, Serena
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2488356/
https://www.ncbi.nlm.nih.gov/pubmed/18590575
http://dx.doi.org/10.1186/1471-2407-8-187